What is Nrf2?
adapted from LifeVantage Science Newsletter
Every second of every day of our life, our cells are bombarded by toxins that are produced when we consume food or take in oxygen.
These toxins, known as oxidants or free radicals, can wreak havoc on all components of our cells, including lipids, proteins and our DNA.
Our bodies are designed to fight off these free radicals with survival genes. But by the time a person reaches age 20, the number of free radicals produced increases, while the number of defensive genes to fight off these free radicals decreases.
This leads to oxidative stress. Oxidative stress contributes to the symptoms of aging.
Critical to the fight against oxidative stress is the protein messenger Nrf2.
In the words of LifeVantage Chief Science Officer Dr. Joe McCord, Nrf2 “significantly modulates the expression of more than 1,000 survival genes, enabling our body to cope with oxidative stress and other kinds of stress as well.”
Further, the website devoted to dispensing info about Nrf2 says, “Nrf2 is a powerful protein that is latent within each cell in the body, unable to move or operate until it is released by an Nrf2 activator. Once released it migrates into the cell nucleus and bonds to the DNA at the location of the Antioxidant Response Element (ARE) or also called hARE (Human Antioxidant Response Element) which is the master regulator of the total antioxidant system that is available in ALL human cells.”
Nrf2 can switch on protective genes and switch off genes that have a negative impact on health.
There are ways to call Nrf2 into action. Certain foods, especially fruits and vegetables such as broccoli, will give you a brief stimulation of Nrf2 for approximately 24 hours. But there is another way to activate Nrf2, one that is much, much more powerful than antioxidants you can get by consuming fruits or vegetables.
Protandim®, the Nrf2 Synergizer®, induces the body to produce more of these powerful, natural antioxidant enzymes. When Protandim turns on the switch to produce these enzymes, each new enzyme molecule can eliminate up to 1 million free radicals per second.